BIOT105 Introduction to Biotechnology

Are there any programs available that can compare chromosomal sequences between two or more species?

Paralogous sequence quantification method

This method offers a chance of examining the gene organization and the discovery of the same gene in a species. The paralogous gene is identified in a procedural method using a browser known as the genome. It examines related chromosomal genes in a species.

VISTA web server

It is a high tooled software for comparing similar genomic sequences. It consists of two modules. The first module is for long genomic sequence alignment and the second is for visualization and element identification (Frazer et al ,2004)

References

Frazer, K. A., Pachter, L., Poliakov, A., Rubin, E. M., & Dubchak, I. (2004). VISTA: computational tools for comparative genomics. Nucleic acids research, 32(suppl_2), W273-W279.

Cheng, J. F., Priest, J. R., & Pennacchio, L. A. (2007). Comparative Genomics. In Cardiac Gene Expression (pp. 229-251). Humana Press.

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